Posted on: December 2, 2003
To clone hair one has to have competent cells, able to transform into cells of hair follicle. These cells should be stem cells.
Bone marrow is a well known source of stem cells. However, until recently it has not been shown that bone marrow stem cells can form actual skin and hairs.
In recently reported experiment on mice, bone marrow cells from adult green fluorescent protein (GFP)-transgenic mice (all cells in these mice are fluorescent with green) were transplanted in a mixture of embryonic mouse skin cells. Within 3 weeks, fully differentiated skin with hair was reconstituted.
Green cells were found in the epidermis, hair follicles, sebaceous glands, and dermis.
Additional experiments confirmed that the bone marrow cells had differentiated into epidermal keratinocytes, sebaceous gland cells, hair follicle cells and others. |
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